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51.
World Journal of Microbiology and Biotechnology - 相似文献
52.
OBJECTIVE: To determine the effect of inequality in income between communities independent of household income on individual all cause mortality in the United States. DESIGN: Longitudinal cohort study. SUBJECTS: A nationally representative sample of 14,407 people aged 25-74 years in the United States from the first national health and nutrition examination survey. SETTING: Subjects were followed from initial interview in 1971-5 until 1987. Complete follow up information was available for 92.2% of the sample. MAIN OUTCOME MEASURES: Relation between both household income and income inequality in community of residence and individual all cause mortality at follow up was examined with Cox proportional hazards survival analysis. RESULTS: Community income inequality showed a significant association with subsequent community mortality, and with individual mortality after adjustment for age, sex, and mean income in the community of residence. After adjustment for individual household income, however, the association with mortality was lost. CONCLUSIONS: In this nationally representative American sample, family income, but not community income inequality, independently predicts mortality. Previously reported ecological associations between income inequality and mortality may reflect confounding between individual family income and mortality. 相似文献
53.
An imported thylakoid protein accumulates in the stroma when insertion into thylakoids is inhibited 总被引:16,自引:0,他引:16
The light-harvesting chlorophyll a/b protein (LHCP) is synthesized in the cytosol as a precursor (pLHCP) that is imported into chloroplasts and assembled into thylakoid membranes. Under appropriate conditions, either pLHCP or LHCP will integrate into isolated thylakoids. We have identified two situations that inhibit integration in this assay. Ionophores and uncouplers inhibited integration up to 70%. Carboxyl-terminal truncations of pLHCP also interfered with integration. A 22-residue truncation reduced integration to about 25% of control, whereas a 93 residue truncation completely abolished it. When pLHCP was imported into chloroplasts in the presence of uncouplers or when truncated forms of pLHCP were used, significant amounts of the imported proteins failed to insert into thylakoids and instead accumulated in the aqueous stroma. Accumulation of stromal LHCP occurred at uncoupler concentrations required to dissipate the trans-thylakoid proton electrochemical gradient and was enhanced at reduced levels of ATP. The latter effect may be a secondary consequence of a reduction in ATP-dependent degradation within the stroma. These results indicate that the stroma is an intermediate location in the LHCP assembly pathway and provide the first evidence for a soluble intermediate during biogenesis of a chloroplast membrane protein. 相似文献
54.
55.
1. Although preference–performance relationships in insects are typically studied in a bi-trophic context, it is well known that host plants can affect both the preference and performance of natural enemies of herbivorous insects. 2. This study presents evidence from field and laboratory studies that two species of milkweeds, the putatively less defended Asclepias incarnata and the putatively more defended Asclepias syriaca, differentially affect adult oviposition and larval performance in Aphidoletes aphidimyza, an aphid-feeding predatory midge, independent of aphid density. 3. Host plant species affected predatory fly larvae abundance by a factor of 50 in the field and a factor of 8 in the laboratory. Larval and adult emergence rates in our laboratory studies provided strong evidence for reduced performance on A. syriaca. Oviposition in choice and no-choice settings provided some evidence for preference for A. incarnata, and a potentially suppressive effect of A. syriaca. 4. The results provide limited support for the hypothesis that natural selection can lead to positive correlations between adult oviposition preferences and larval performance upon various food sources, even when predatory insects oviposit onto host plants of their herbivorous prey. 5. Preference and performance are not perfectly aligned in this system, however, because ovipositing females do not reject A. syriaca entirely. Potential explanations for mismatches between preference and performance in this system include the neural constraints associated with being a generalist, adaptive time-limited foraging strategies, and unique evolutionary histories of laboratory colonies compared with wild insects. 相似文献
56.
Andreas König 《European Journal of Wildlife Research》2008,54(1):101-109
Throughout Central Europe, foxes have taken over urban areas as their habitat. In Southern Germany, these foxes are also carriers
of the small fox tapeworm, which causes a serious zoonotic infection in humans. Therefore, a survey was carried out in a suburb
of the city of Munich. A postal questionnaire was used to analyse the attitudes, opinions and fears of these participants
towards their urban foxes and the background to these attitudes. Questionnaires were sent to all households with gardens and
collected in again via the community council. Seven hundred and seventy-nine or 31% of questionnaires were returned. Only
a few people are afraid of the fox itself; however, 55% are afraid of the fox tapeworm. Worming the animals is the preferred
counter-measure, with 81% in favour. The majority of inhabitants are pleased to see a fox in the community and feel the animals
have a right to live. People are afraid of the tapeworm either because they have children in the household or because of increased
knowledge of the subject or because it has increasingly become an issue. On the basis of the results of this study, it is
to be expected that radical solutions such as killing the foxes are unlikely to be accepted among the population. Worming
of the foxes does, however, meet with general approval. 相似文献
57.
Anne F Mannion Stephane Kämpfen Urs Munzinger Ines Kramers-de Quervain 《Arthritis research & therapy》2009,11(5):R139-13
Introduction
Patient's expectations are variably reported to influence self-rated outcome and satisfaction after medical treatment; this prospective study examined which of the following was the most important unique determinant of global outcome/satisfaction after total knee arthroplasty (TKA): baseline expectations; fulfilment of expectations; or current symptoms and function. 相似文献58.
Robert M Bennett Ronald Friend Kim D Jones Rachel Ward Bobby K Han Rebecca L Ross 《Arthritis research & therapy》2009,11(4):R120-14
Introduction
The Fibromyalgia Impact Questionnaire (FIQ) is a commonly used instrument in the evaluation of fibromyalgia (FM) patients. Over the last 18 years, since the publication of the original FIQ, several deficiencies have become apparent and the cumbersome scoring algorithm has been a barrier to widespread clinical use. The aim of this paper is to describe and validate a revised version of the FIQ: the FIQR. 相似文献59.
SUMMARY The current concept of the order Asaphida was proposed to accommodate some Cambrian and Ordovician trilobite clades that are characterized by the possession of a ventral median suture. The family Tsinaniidae was recently suggested to be a member of the order Asaphida on the basis of its close morphological similarity to Asaphidae. Postembryonic development of the tsinaniid trilobite, Tsinania canens , from the Furongian (late Cambrian) Hwajeol Formation of Korea, reveals that this trilobite had an adult-like protaspis. Notable morphological changes with growth comprise the effacement of dorsal furrows, sudden degeneration of pygidial spines, regression of genal spines, and loss of a triangular rostral plate to form a ventral median suture. Programmed cell death may be responsible for degenerating the pygidial and genal spines during ontogeny. Morphological changes with growth, such as the loss of pygidial spines, modification of pleural tips, and effacement of dorsal furrows, suggest that T. canens changed its life mode during ontogeny from benthic crawling to infaunal. The protaspid morphology and the immature morphology of T. canens retaining genal and pygidial spines suggest that tsinaniids bear a close affinity to leiostegioids of the order Corynexochida. Accordingly, development of a ventral median suture in T. canens demonstrates that the ventral median suture could have evolved polyphyletically, and thus the current concept of the order Asaphida needs to be revised. 相似文献
60.
F. L. Laksmana P. J. A. Hartman Kok H. Vromans H. W. Frijlink K. Van der Voort Maarschalk 《AAPS PharmSciTech》2009,10(3):732-742
Next to the coating formulation, process conditions play important roles in determining coating quality. This study aims to
develop an operational window that separates layering from agglomeration regimes and, furthermore, the one that leads to the
best coating quality in a fluidized bed coater. The bed relative humidity and the droplet size of the coating aerosol were
predicted using a set of engineering models. The coating quality was characterized using a quantitative image analysis method,
which measures the coating thickness distribution, the total porosity, and the pore size in the coating. The layering regime
can be achieved by performing the coating process at a certain excess of the viscous Stokes number (ΔSt
v). This excess is dependent on the given bed relative humidity and droplet size. The higher the bed relative humidity, the
higher is the ΔSt
v required to keep the process in the layering regime. Further, it is shown that using bed relative humidity and droplet size
alone is not enough to obtain constant coating quality. The changes in bed relative humidity and droplet size have been identified
to correlate to the fractional area of particles sprayed per unit of time. This parameter can effectively serve as an additional
parameter to be considered for a better control on the coating quality. High coating quality is shown to be achieved by performing
the process close to saturation and spraying droplets small enough to obtain high spraying rate, but not too small to cause
incomplete coverage of the core particles. 相似文献